2021 USCAP Maude Abbott Lecture - Neuroendocrine Carcinomas of Head and Neck:
Tsogolo Lakale, Lapano ndi Lotheka

BRUCE M. WENIG, MD

Chairman ndi Senior Member
Dipatimenti ya Matenda
Moffitt Khansa Center
Pulofesa wa Sayansi ya Oncological
University of South Florida
Tampa, Florida

Nthawi yothamanga: 1 ora 26 Mphindi

ZOKHUDZA PHUNZIRO

Neuroendocrine neoplasms (NEN) imapezeka pafupifupi m'chiwalo chilichonse. Kukula kwa embryologic kwa NEN kwakhala nkhani yotsutsana ngati pali kapena palibe chiyambi cha neural crest. Pansi pamalingaliro amtundu wamba wa neural crest chiyambi, kukhalapo kwa njira yodziwika bwino yazachilengedwe m'maselo a neuroendocrine opangidwa ndi kutengeka ndi decarboxylation ya amine precursors adanenedwa kuti maselowa adziwike ndi histochemically ndikupangitsa kugwiritsa ntchito mawu akuti APUD (Amine Precursor). Uptake ndi Decarboxylation) kufotokoza ma cell omwe ali mu dongosolo lino. Kafukufuku wotsatira adasokoneza chiyambi wamba wa neural crest ndipo gulu la Disspersed Neuroendocrine Cell System lidatengera NEN. Gulu la NEN lasintha momwe machitidwe apano posatengera komwe adachokera akuti agwiritse ntchito nomenclature yokhazikitsidwa ndi m'mimba ndi kapamba NEN. Kupatula thirakiti la m'mimba, kapamba ndi mapapo, chigawo cha mutu ndi khosi ndi amodzi mwa malo omwe amapezeka kwambiri ku NEN ndipo m'chigawo chino neuroendocrine carcinoma ndi mtundu wodziwika bwino wa NEN. Nkhaniyi ifotokoza za neuroendocrine carcinomas ya mutu ndi khosi kuwunikanso mawonekedwe awo azachipatala ndikukambilana za kuphatikizidwa kwawo m'gulu lofananira lomwe lakonzedwa pa tsamba lina la NEN.

ZINTHU ZOPHUNZIRA

1. Kambiranani za chitukuko cha embryologic cha neuroendocrine neoplasms
2. Fotokozani njira zodziwira matenda ammutu ndi khosi neuroendocrine neoplasms kusiyanitsa izi ndi zomwe zili patsamba lina la NEN
3. Dziwani ngati dongosolo lodziwika bwino la NEN likugwira ntchito kumutu ndi khosi NEN